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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC5A11
All Species:
4.24
Human Site:
S580
Identified Species:
10.37
UniProt:
Q8WWX8
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWX8
NP_443176.2
675
74036
S580
A
P
L
S
L
T
L
S
Q
N
G
M
P
E
A
Chimpanzee
Pan troglodytes
XP_515093
664
73434
G583
E
E
E
N
I
Q
E
G
P
K
E
T
T
E
I
Rhesus Macaque
Macaca mulatta
XP_001098708
675
74047
S580
A
P
L
S
L
A
L
S
Q
N
G
M
P
E
A
Dog
Lupus familis
XP_547085
748
81617
I654
A
T
P
L
P
L
T
I
S
Q
N
G
T
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0E3
673
73779
L579
E
T
P
L
S
L
T
L
S
Q
N
G
T
T
E
Rat
Rattus norvegicus
Q9Z1F2
673
73587
I579
E
N
P
L
S
L
T
I
S
Q
N
G
T
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414862
675
74403
D590
E
R
P
A
L
Q
I
D
I
S
I
A
S
E
N
Frog
Xenopus laevis
NP_001079025
673
74118
D583
N
G
I
S
V
V
E
D
I
S
E
E
P
H
T
Zebra Danio
Brachydanio rerio
A8WHP3
657
72206
G576
D
P
W
A
K
P
A
G
S
D
L
S
T
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798065
645
71497
V565
Q
D
L
S
I
S
E
V
Q
E
L
K
E
K
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.8
97.1
80.2
N.A.
86.3
85.4
N.A.
N.A.
70.6
69.1
54.9
N.A.
N.A.
N.A.
N.A.
54.5
Protein Similarity:
100
69
98.2
85.8
N.A.
92.8
92.1
N.A.
N.A.
83.4
81.1
73.3
N.A.
N.A.
N.A.
N.A.
73.1
P-Site Identity:
100
6.6
93.3
6.6
N.A.
0
0
N.A.
N.A.
13.3
13.3
6.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
20
93.3
6.6
N.A.
0
0
N.A.
N.A.
33.3
33.3
20
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
0
0
20
0
10
10
0
0
0
0
10
0
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
0
0
0
0
20
0
10
0
0
0
0
0
% D
% Glu:
40
10
10
0
0
0
30
0
0
10
20
10
10
40
40
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
20
0
0
20
30
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
10
0
20
0
10
20
20
0
10
0
0
0
10
% I
% Lys:
0
0
0
0
10
0
0
0
0
10
0
10
0
10
0
% K
% Leu:
0
0
30
30
30
30
20
10
0
0
20
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% M
% Asn:
10
10
0
10
0
0
0
0
0
20
30
0
0
0
10
% N
% Pro:
0
30
40
0
10
10
0
0
10
0
0
0
30
10
0
% P
% Gln:
10
0
0
0
0
20
0
0
30
30
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
40
20
10
0
20
40
20
0
10
10
0
0
% S
% Thr:
0
20
0
0
0
10
30
0
0
0
0
10
50
30
10
% T
% Val:
0
0
0
0
10
10
0
10
0
0
0
0
0
0
10
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _